Drug screening is a step in the modern drug development process to test and obtain compounds with specific physiological activity, and to select compounds with high biological activity, pharmacological action, and medicinal value from a large number of compounds or new compounds by standardized experimental means. It requires a cross-sectional comparison of the physiological activities of different compounds, so the experimental protocols for drug screening need to be standardized and quantified. With the development of combinatorial and computational chemistry, people started to have the ability to synthesize and isolate multiple compounds on a large scale in a short period of time, and thus drug screening has gradually become one of the main ways to discover lead compounds in the modern new drug development process. The main techniques are genomics, proteomics, metabolomics, computational biology, biochip technology, microfluidic chip technology, and other methods to perform the process of drug preference within a certain selectable range.
Ace Infectious has many years of experience in antiparasitic drug testing services and can provide a variety of services and solutions for clients based on their specific needs for experimental design and planning. Ace Infectious has an experienced team and advanced instrumentation to provide a wide range of large-scale anti-parasitic drug screening services, including high-throughput screening and high-content screening, and can undertake customized services to provide valuable information for the identification and optimization of lead compounds.
Service Options for Anti-parasitic Drugs Screening
- Build a technical platform for antiparasitic drug screening and provide technical consulting services.
- Establish high-throughput/high-content screening technology and various in vivo and ex vivo screening models.
- Screening for suitable targets or biomarkers
- Preparation of parasite models and detection systems
- Screening of potential anti-parasitic drug compounds
- Evaluation of compound safety and toxicity
Service Types for Anti-parasitic Drugs Screening
High-Throughput Screening (HTS) is a microplate format, automated operating system, and assay instrument for experimental manipulation and data collection at the molecular or cellular level, allowing samples to be assayed at the same time and data to be analyzed and processed by computer. Our high-throughput devices allow the use of 384-well plates and a variety of assay techniques such as chemiluminescence, fluorescence, absorbance, etc. to measure the permeability, stability, metabolic pathways, metabolites, and cytotoxicity of compounds at the molecular or cellular level as well as in 3D cultured cell models.
Learn more: antiparasitic drug screening technical consulting services